Infasurf/Calfactant (Patient Information)

What is Infasurf (calfactant)?

Calfactant is used to treat or prevent respiratory distress syndrome (RDS) in a premature baby whose lungs have not fully developed. Calfactant causes few side effects. There is a possibility that the baby will have breathing difficulties during the calfactant treatment, and these problems may require further treatment by your baby's health care team. Your baby will remain under constant supervision during treatment with calfactant.

How is calfactant given?
  • Calfactant is given directly into the baby's lungs through a breathing tube. Your baby will receive this medication in a neonatal intensive care unit (NICU) or similar hospital setting.
  • The breathing tube is connected to a ventilator (a machine that moves air in and out of the lungs to help your baby breathe easier and get enough oxygen).
  • Calfactant is given as soon as possible after the baby's birth, usually within 30 minutes.
  • Calfactant is usually given every 12 hours for up to 3 doses.
  • Your baby's breathing, blood pressure, oxygen levels, and other vital signs will be watched closely during treatment with calfactant.

What happens if an overdose is given?

Since calfactant is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. However, an overdose of calfactant is not expected to produce life-threatening symptoms.